Article
Circulating mucosal-associated invariant T cells in subjects with recurrent urinary tract infections are functionally impaired.
Immunity, inflammation and disease - 1 Mar 2020
Terpstra Matty L, Remmerswaal Ester B M, van Aalderen Michiel C, Wever Joyce J, Sinnige Marjan J, van der Bom-Baylon Nelly D, Bemelman Frederike J, Geerlings Suzanne E
Abstract excerpt
BACKGROUND: Urinary tract infection recurrence is common, particularly in women and immunocompromised patients, such as renal transplant recipients (RTRs). Mucosal-associated invariant T (MAIT) cells play a role in the antibacterial response by recognizing bacterial riboflavin metabolites produced by bacteria such as Escherichia coli. Here, we investigated whether MAIT cells are involved in the pathogenesis of...
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