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Article

MAIT cells accumulate in placental intervillous space and display a highly cytotoxic phenotype upon bacterial stimulation.

Scientific reports - 21 Jul 2017

Solders Martin, Gorchs Laia, Erkers Tom, Lundell Anna-Carin, Nava Silvia, Gidlöf Sebastian, Tiblad Eleonor, Magalhaes Isabelle, Kaipe Helen

Abstract excerpt

During pregnancy, the maternal immune system must tolerate the developing foetus, and yet retain a potent antimicrobial response to prevent infections. Mucosal associated invariant T (MAIT) cells recognize microbial-derived vitamin B metabolites presented on the MR1 molecule, but their presence and function at the foetal-maternal interface is not known. We here isolated mononuclear cells from paired samples of...

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Identifiers

PMID: 28733576
DOI: 10.1038/s41598-017-06430-6
PMCID: PMC5522401

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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