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Article

Examination of a Second Region of the HIV Type 1 Genome Reveals Additional Cases of Superinfection

26 Aug 2008

Abstract excerpt

HIV-1 superinfection may occur at a rate similar to that of initial infection, raising concerns for HIV-1 vaccine strategies predicated on eliciting immune responses similar to those in natural infection. Because of the high rate of recombination during HIV-1 replication, studies examining only one region of the HIV-1 genome are likely to miss cases of HIV-1 superinfection. We examined HIV-1 gag sequences from 14...

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PMID: 18729772
DOI: 10.1089/aid.2008.0100

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