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Article

Different β-cell secretory phenotype in non-obese compared to obese early type 2 diabetes.

Diabetes/metabolism research and reviews - 1 Jul 2020

Gudipaty Lalitha, Rosenfeld Nora K, Fuller Carissa S, Cuchel Marina, Rickels Michael R

Abstract excerpt

BACKGROUND: Type 2 diabetes (T2D) is characterized by impaired tissue sensitivity to insulin action (ie, insulin resistance) and impaired β-cell insulin secretion. Because obesity contributes importantly to the development of insulin resistance, we sought to determine whether insulin secretory defects would predominate in non-obese compared to obese T2D. METHODS: We measured β-cell function and secretory capacity...

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Identifiers

PMID: 32017362
DOI: 10.1002/dmrr.3295
PMCID: PMC7864552

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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