Normal physiology and phenotypic characterization of beta-cell function in subjects at risk for non-insulin-dependent diabetes mellitus.

Article

Normal physiology and phenotypic characterization of beta-cell function in subjects at risk for non-insulin-dependent diabetes mellitus.

Diabetic medicine : a journal of the British Diabetic Association - 1 Sept 1996

Porte D

Abstract excerpt

Major genes for NIDDM appear to be rare. Therefore, phenotypic characterization of the pathophysiological changes contributing to hyperglycaemia are assuming increasing importance. Assessment of beta-cell function has been hampered by two major confounding factors during functional testing: varia...

Topics

Blood Glucose
C-Peptide
Diabetes Mellitus, Type 2
Humans
Insulin
Insulin Secretion
Islets of Langerhans
Phenotype
Proinsulin
Risk Factors

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