Article
Visceral fat and beta cell function in non-diabetic humans.
Diabetologia - 1 Oct 2005
Gastaldelli A, Sironi A M, Ciociaro D, Positano V, Buzzigoli E, Giannessi D, Lombardi M, Mari A, Ferrannini E
Abstract excerpt
AIMS/HYPOTHESIS: Preferential visceral adipose tissue (VAT) accumulation has been clearly associated with insulin resistance. In contrast, the impact of visceral obesity on beta cell function is controversial. METHODS: In 62 non-diabetic women and men (age 24-69 years, BMI 21-39 kg/m2), we measured VAT and subcutaneous adipose tissue (SAT) fat mass by magnetic resonance imaging. We also measured insulin secretion...
Topics
- Adipose Tissue
- Adult
- Anthropometry
- Area Under Curve
- Body Weight
- C-Peptide
- Female
- Glucose
- Glucose Intolerance
- Glucose Tolerance Test
- Humans
- Insulin
- Insulin Secretion
- Insulin-Secreting Cells
- Lipids
- Magnetic Resonance Imaging
- Male
- Models, Biological
