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Psammomys Obesus, a Model for Environment-Gene Interactions in Type 2 Diabetes

1 Dec 2005

Abstract excerpt

Type 2 diabetes is characterized by insulin resistance and progressive beta-cell failure. Deficient insulin secretion, with increased proportions of insulin precursor molecules, is a common feature of type 2 diabetes; this could result from inappropriate beta-cell function and/or reduced beta-cell mass. Most studies using tissues from diabetic patients are retrospective, providing only limited information on the...

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PMID: 16306331
DOI: 10.2337/diabetes.54.suppl_2.s137

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