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Article

Glucocorticoids induce differentiation of a specifically activated, anti-inflammatory subtype of human monocytes.

Blood - 1 Feb 2007

Ehrchen Jan, Steinmüller Lars, Barczyk Katarzyna, Tenbrock Klaus, Nacken Wolfgang, Eisenacher Martin, Nordhues Ursula, Sorg Clemens, Sunderkötter Cord, Roth Johannes

Abstract excerpt

Monocytes and macrophages may either promote or down-regulate inflammatory reactions depending on their state of activation. The effects of glucocorticoids (GCs), the most widely used immunosuppressive drugs, on monocytes are currently not well defined. By analyzing the GC-induced expression pattern in human monocytes by microarray technology, we identified for the first time GC-dependent regulation of 133 genes,...

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Source

Identifiers

PMID: 17018861
DOI: 10.1182/blood-2006-02-001115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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