Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

G-CSF mobilizes CD34 <sup>+</sup> regulatory monocytes that inhibit graft-versus-host disease

1 Apr 2015

Abstract excerpt

Granulocyte colony-stimulating factor (G-CSF) is routinely used to collect peripheral blood stem cells (PBSCs) from healthy donors for allogeneic hematopoietic stem cell transplantation (allo-HSCT). We show that, in both humans and mice, G-CSF mobilizes a subset of CD34(+) cells with mature monocyte features. These cells, which are phenotypically and functionally conserved in mice and humans, are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hematopoietic Stem Cell Transplantation
Share to Immune cells in cancer
Share to Mesenchymal stem cell research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25834108
DOI: 10.1126/scitranslmed.3010435

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

G-CSF mobilizes CD34 <sup>+</sup> regulatory monocytes that inhibit graft-versus-host diseasePMID 25834108Read ↗

A Pilot Study of Circulating Monocyte Subsets in Patients Treated with Stem Cell Transplantation for High-Risk Hematological Malignancies.Semantic proximity Read ↗

Increased CD83 expression of CD34-positive monocytes in donors during peripheral blood stem cell mobilization in humans.Semantic proximity Read ↗

Immature monocytes from G-CSF-mobilized peripheral blood stem cell collections carry surface-bound IL-10 and have the potential to modulate alloreactivity.Semantic proximity Read ↗

Generation of mature murine monocytes from heterogeneous bone marrow and description of their properties.Semantic proximity Read ↗

Blood Monocytes: Development, Heterogeneity, and Relationship with Dendritic CellsSemantic proximity Read ↗

Inflammatory monocytes promote pre-engraftment syndrome and tocilizumab can therapeutically limit pathology in patients.Semantic proximity Read ↗

CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responsesSemantic proximity Read ↗

Clinical significance of monocyte heterogeneitySemantic proximity Read ↗

Donor monocyte-derived macrophages promote human acute graft versus host diseaseSemantic proximity Read ↗

Donor monocyte–derived macrophages promote human acute graft-versus-host diseaseSemantic proximity Read ↗

Monocytes from mobilized stem cells inhibit T cell function.Semantic proximity Read ↗

Identification of monocyte-like precursors of granulocytes in cancer as a mechanism for accumulation of PMN-MDSCsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.