Article
Glucocorticoids induce an activated, anti-inflammatory monocyte subset in mice that resembles myeloid-derived suppressor cells.
Journal of leukocyte biology - 1 Sept 2008
Varga Georg, Ehrchen Jan, Tsianakas Athanasios, Tenbrock Klaus, Rattenholl Anke, Seeliger Stephan, Mack Matthias, Roth Johannes, Sunderkoetter Cord
Abstract excerpt
Glucocorticoids (GC) are still the most widely used immunosuppressive agents in clinical medicine. Surprisingly, little is known about the mechanisms of GC action on monocytes, although these cells exert pro- and anti-inflammatory effects. We have shown recently that GC induce a specific monocyte...
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