Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NFKB1 gene single-nucleotide polymorphisms: implications for graft-versus-host disease in allogeneic hematopoietic stem cell transplantation.

Annals of hematology - 1 Mar 2020

Kuba Adam, Raida Ludek, Mrazek Frantisek, Schneiderova Petra, Kriegova Eva, Langova Katerina, Furst Tomas, Furstova Jana, Faber Edgar, Papajik Tomas

Abstract excerpt

Graft-versus-host disease (GVHD) represents a significant cause of mortality after allogeneic hematopoietic stem cell transplantation (HSCT). NF-kB system is a master regulator of innate immunity responses. It controls the expression of various cytokines and chemokines many of which are involved in GVHD pathogenesis. Chemo(radio) therapy administered during conditioning induces DNA damage and activates DNA damage...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Allografts
Share to Disease-Free Survival

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Graft vs Host Disease

Share to Hematopoietic Stem Cell Transplantation

Share to NF-kappa B p50 Subunit

Share to Pilot Projects

Share to Polymorphism, Single Nucleotide

Share to Survival Rate

Source

Identifiers

PMID: 32002656
DOI: 10.1007/s00277-020-03935-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NFKB1 gene single-nucleotide polymorphisms: implications for graft-versus-host disease in allogeneic hematopoietic stem cell transplantation.PMID 32002656Read ↗

Polymorphisms in the base excision repair pathway and graft-versus-host disease.Semantic proximity Read ↗

Graft versus Host Disease: From Basic Pathogenic Principles to DNA Damage Response and Cellular SenescenceSemantic proximity Read ↗

Multiple single-nucleotide polymorphism-based risk model for clinical outcomes after allogeneic stem-cell transplantation, especially for acute graft-versus-host disease.Semantic proximity Read ↗

Impact of NF-κB gene polymorphism on allograft outcome in Hispanic renal transplant recipients.Semantic proximity Read ↗

Risk stratification of organ-specific GVHD can be improved by single-nucleotide polymorphism-based risk models.Semantic proximity Read ↗

Cellular senescence marker p16INK4a and NFKB1 gene polymorphisms in lower gastro-intestinal acute graft versus host disease.Semantic proximity Read ↗

Personalized Medicine for Kidney Transplantation: Association of Graft Survival and Acute Transplant Rejection with Genetic Variation in B Cell Activating Factor System Signaling.Semantic proximity Read ↗

Single nucleotide polymorphisms and outcome risk in unrelated mismatched hematopoietic stem cell transplantation: an exploration study.Semantic proximity Read ↗

Genetic Polymorphisms of Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4) and clinical outcomes post-allogeneic hematopoietic stem cell transplantation: A systematic review and meta-analysis.Semantic proximity Read ↗

Replication and validation of genetic polymorphisms associated with survival after allogeneic blood or marrow transplant.Semantic proximity Read ↗

Association study of candidate DNA-repair gene variants and acute graft versus host disease in pediatric patients receiving allogeneic hematopoietic stem-cell transplantation.Semantic proximity Read ↗

The NFKB1 Promoter Polymorphism (-94ins/delATTG) Is Associated with Susceptibility to Cytomegalovirus Infection after Kidney Transplantation and Should Have Implications on CMV Prophylaxis Regimens.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.