Article
Single nucleotide polymorphisms and outcome risk in unrelated mismatched hematopoietic stem cell transplantation: an exploration study.
Blood - 28 Jun 2012
Harkensee Christian, Oka Akira, Onizuka Makoto, Middleton Peter G, Inoko Hidetoshi, Hirayasu Kouyuki, Kashiwase Koichi, Yabe Toshio, Nakaoka Hirofumi, Gennery Andrew R, Ando Kiyoshi, Morishima Yasuo
Abstract excerpt
Genetic risk factors contribute to adverse outcome of hematopoietic stem cell transplantation (HSCT). Mismatching of the HLA complex most strongly determines outcomes, whereas non-HLA genetic polymorphisms are also having an impact. Although the majority of HSCTs are mismatched, only few studies have investigated the effects of non-HLA polymorphisms in the unrelated HSCT and HLA-mismatched setting. To understand...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
