Article
Impact of NF-κB gene polymorphism on allograft outcome in Hispanic renal transplant recipients.
Transplant immunology - 1 Jan 2013
Vu Don, Tellez-Corrales Eglis, Sakharkar Prashant, Kissen Michael Scott, Shah Tariq, Hutchinson Ian, Min David I
Abstract excerpt
BACKGROUND: The dimeric NF-κB transcription factors play critical roles in diverse cellular processes including adaptive and innate immunity, cell differentiation, proliferation and apoptosis. It regulates the expression of numerous genes that play a key role in the inflammatory response during kidney allograft rejection. This study aims to determine the association of NF-κB gene polymorphisms with allograft...
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