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Analysis of runs of homozygosity and their relationship with inbreeding in five cattle breeds farmed in Italy.

Animal genetics - 1 Apr 2015

Marras Gabriele, Gaspa Giustino, Sorbolini Silvia, Dimauro Corrado, Ajmone-Marsan Paolo, Valentini Alessio, Williams John L, Macciotta Nicolò P P

Abstract excerpt

Increased inbreeding is an inevitable consequence of selection in livestock populations. The analysis of high-density single nucleotide polymorphisms (SNPs) facilitates the identification of long and uninterrupted runs of homozygosity (ROH) that can be used to identify chromosomal regions that are identical by descent. In this work, the distribution of ROH of different lengths in five Italian cattle breeds is...

Topics

Animals
Cattle
Genotype
Homozygote
Inbreeding
Italy
Linear Models
Linkage Disequilibrium
Male
Pedigree
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25530322
DOI: 10.1111/age.12259

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