Article
A Cell Fate Switch in the Caenorhabditis elegans Seam Cell Lineage Occurs Through Modulation of the Wnt Asymmetry Pathway in Response to Temperature Increase.
Genetics - 1 Apr 2020
Hintze Mark, Koneru Sneha L, Gilbert Sophie P R, Katsanos Dimitris, Lambert Julien, Barkoulas Michalis
Abstract excerpt
Populations often display consistent developmental phenotypes across individuals despite inevitable biological stochasticity. Nevertheless, developmental robustness has limits, and systems can fail upon change in the environment or the genetic background. We use here the seam cells, a population of epidermal stem cells in Caenorhabditis elegans, to study the influence of temperature change and genetic variation...
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