Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Significance of Myelodysplasia-Related Mutations and the Genetic Landscape of Acute Leukemias of Ambiguous Lineage.

International journal of laboratory hematology - 1 Jun 2026

Kirtek Timothy J, Weinberg Olga K

Abstract excerpt

The recent fifth edition WHO classification and ICC classification systems have moved further toward genetically defined classifications of acute leukemias. Both now recognize myelodysplasia-related (MR) mutations as defining of MDS-related AML (AML-MR). Acute leukemias of ambiguous lineage (ALAL) are a heterogenous group of acute leukemias characterized by leukemic blasts that either express markers of multiple...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Core Binding Factor Alpha 2 Subunit
Share to ASXL1 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to RUNX1 gene

Share to Leukemia, Myeloid, Acute

Share to Mutation

Share to Myelodysplastic Syndromes

Source

Open in PubMed Open full text

Identifiers

PMID: 40637261
DOI: 10.1111/ijlh.14529
PMCID: PMC13155273

Genes

ASXL1
RUNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Significance of Myelodysplasia-Related Mutations and the Genetic Landscape of Acute Leukemias of Ambiguous Lineage.PMID 40637261Read ↗

Genetic Landscape of Acute Leukemia of Ambiguous Lineage: A Single Cancer Center Experience.Semantic proximity Read ↗

Acute Leukemias of Ambiguous Lineage With RUNX1 Mutations Show Similar Prognosis Compared to Acute Myeloid Leukemia With RUNX1 Mutations: A Study From the Bone Marrow Pathology Group.Semantic proximity Read ↗

Navigating the contested borders between myelodysplastic syndrome and acute myeloid leukemiaSemantic proximity Read ↗

Toward a unified classification of acute myeloid leukemia, myelodysplasia-related: a multicenter retrospective studySemantic proximity Read ↗

How to think about acute leukemia of ambiguous lineageSemantic proximity Read ↗

Genetic Factors in Acute Myeloid Leukemia With Myelodysplasia-Related Changes.Semantic proximity Read ↗

How I Diagnose Acute Leukemia of Ambiguous LineageSemantic proximity Read ↗

The mutational landscape of 18 investigated genes clearly separates four subtypes of myelodysplastic/myeloproliferative neoplasmsSemantic proximity Read ↗

The Genetic Landscape of Myelodysplastic Neoplasm Progression to Acute Myeloid Leukemia.Semantic proximity Read ↗

Acute Myeloid Leukemia with Myelodysplasia-Related Gene MutationsSemantic proximity Read ↗

The association of complex genetic background with the prognosis of acute leukemia with ambiguous lineage.Semantic proximity Read ↗

Diagnosis and Treatment of Patients With Acute Myeloid Leukemia With Myelodysplasia-Related Changes (AML-MRC).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.