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Outcomes of acute myeloid leukemia with myelodysplasia related changes depend on diagnostic criteria and therapy.

American journal of hematology - 1 Jun 2020

Montalban-Bravo Guillermo, Kanagal-Shamanna Rashmi, Class Caleb A, Sasaki Koji, Ravandi Farhad, Cortes Jorge E, Daver Naval, Takahashi Koichi, Short Nicholas J, DiNardo Courtney D, Jabbour Elias, Borthakur Gautam, Naqvi Kiran, Issa Ghayas C, Konopleva Marina, Khoury Joseph D, Routbort Mark, Pierce Sherry, Do Kim-Anh, Bueso-Ramos Carlos, Patel Keyur, Kantarjian Hagop, Garcia-Manero Guillermo, Kadia Tapan M

Abstract excerpt

Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) is a heterogeneous disorder defined by multilineage dysplasia, myelodysplastic syndrome (MDS)-related karyotype, or history of prior MDS. We evaluated 415 patients with AML-MRC treated from 2013 to 2018 and analyzed their clinical outcomes based on the diagnostic criteria of AML-MRC, therapy type and mutation profile. Criteria for AML-MRC...

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Disease-Free Survival

Myelodysplastic Syndromes

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PMID: 32112433
DOI: 10.1002/ajh.25769

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