Article
Inference of population structure using dense haplotype data.
PLoS genetics - 1 Jan 2012
Lawson Daniel John, Hellenthal Garrett, Myers Simon, Falush Daniel
Abstract excerpt
The advent of genome-wide dense variation data provides an opportunity to investigate ancestry in unprecedented detail, but presents new statistical challenges. We propose a novel inference framework that aims to efficiently capture information on population structure provided by patterns of haplotype similarity. Each individual in a sample is considered in turn as a recipient, whose chromosomes are reconstructed...
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