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Article

Affinity improvement of the fully human anti‑TSLP recombinant antibody.

Molecular medicine reports - 1 Feb 2020

Chen Qi, Xian Dequn, Xu Wenfeng, Nian Siji, Yu Hong, Wu Yuchuan, Yuan Qing

Abstract excerpt

Thymic stromal lymphopoietin (TSLP) is a potentially important target for the treatment of asthma and malignancies. However, a fully human antibody reactive with TSLP is currently unavailable for clinical use. In a previous study, a human anti‑TSLP‑single‑chain antibody variable fragment (anti‑TSLP‑scFv) 84 was selected by phage display from a constructed human scFv library. In the present study, a computer...

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Identifiers

PMID: 31974622
DOI: 10.3892/mmr.2019.10880
PMCID: PMC6947841

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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