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Mammalian cell display for rapid screening scFv antibody therapy

23 Sept 2014

Abstract excerpt

Human antibodies are beginning to draw attention for use in immune gene therapy. The efficient generation of effective therapeutic monoclonal antibodies suitable for the treatment of cancers and infectious diseases would be enormously valuable. Antibody display methods are increasingly used to screen human monoclonal antibodies. Here we report the construction of a mammalian cell display method derived from a...

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PMID: 25246434
DOI: 10.1093/abbs/gmu079

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