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Article

Genomic complexity identifies patients with aggressive chronic lymphocytic leukemia.

Blood - 1 Sept 2008

Kujawski Lisa, Ouillette Peter, Erba Harry, Saddler Chris, Jakubowiak Andrzej, Kaminski Mark, Shedden Kerby, Malek Sami N

Abstract excerpt

Chronic lymphocytic leukemia (CLL) has a variable clinical course. Presence of specific genomic aberrations has been shown to impact survival outcomes and can help categorize CLL into clinically distinct subtypes. We studied 178 CLL patients enrolled in a prospective study at the University of Michigan, of whom 139 and 39 were previously untreated and previously treated, respectively. We obtained unbiased,...

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Source

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Identifiers

PMID: 18436738
DOI: 10.1182/blood-2007-07-099432
PMCID: PMC2518900

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