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Article

Genomic imbalance defines three prognostic groups for risk stratification of patients with chronic lymphocytic leukemia.

Leukemia & lymphoma - 1 Apr 2014

Houldsworth Jane, Guttapalli Asha, Thodima Venkata, Yan Xiao Jie, Mendiratta Geetu, Zielonka Tania, Nanjangud Gouri, Chen Weiyi, Patil Sujata, Mato Anthony, Brown Jennifer R, Rai Kanti, Chiorazzi Nicholas, Chaganti R S K

Abstract excerpt

Array comparative genomic hybridization (aCGH) has yet to be fully leveraged in a prognostic setting in chronic lymphocytic leukemia (CLL). Genomic imbalance was assessed in 288 CLL specimens using a targeted array. Based on 20 aberrations in a hierarchical manner, all 228 treatment-naive specimens were classified into a group with poor outcome (20.6%) exhibiting at least one aberration that was univariately...

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Identifiers

PMID: 24047479
DOI: 10.3109/10428194.2013.845882
PMCID: PMC6905429

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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