Article
Genetic mutations in acute myeloid leukemia that influence clinical decisions.
Current opinion in hematology - 1 Mar 2014
Chung Stephen S
Abstract excerpt
PURPOSE OF REVIEW: A plethora of studies over the past two decades have identified many genes that are recurrently mutated in acute myeloid leukemia (AML). Although great advances have been made in understanding the role of these mutated genes in AML disease pathogenesis, to date relatively few have been demonstrated to have direct clinical relevance. RECENT FINDINGS: Genomic techniques have allowed for the...
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