Article
Molecular genetics of AML.
Best practice & research. Clinical haematology - 1 Dec 2012
Link Daniel C
Abstract excerpt
In the past decade, a series of technological advances have revolutionized our ability to interrogate cancer genomes, culminating in whole-genome sequencing, which provides genome-wide coverage at a single base-pair resolution. To date, the tumor genome has been sequenced in nearly 40 cases of acute myeloid leukemia (AML). On average, each AML genome contains approximately 400 mutations, including 6-26 coding...
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