Article
Katanin p60-like1 promotes microtubule growth and terminal dendrite stability in the larval class IV sensory neurons of Drosophila.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 22 Aug 2012
Stewart Andrea, Tsubouchi Asako, Rolls Melissa M, Tracey W Daniel, Sherwood Nina Tang
Abstract excerpt
Dendrite shape is considered a defining component of neuronal function. Yet, the mechanisms specifying diverse dendritic morphologies, and the extent to which their function depends on these morphologies, remain unclear. Here, we demonstrate a requirement for the microtubule-severing protein katanin p60-like 1 (Kat-60L1) in regulating the elaborate dendrite morphology and nocifensive functions of Drosophila...
Topics
- Adenosine Triphosphatases
- Animals
- Animals, Genetically Modified
- Brain
- Cell Differentiation
- Dendrites
- Drosophila
- Drosophila Proteins
- Gene Expression Regulation, Developmental
- Katanin
- Larva
- Luminescent Proteins
- Microtubule-Associated Proteins