Article
The SLC36 transporter Pathetic is required for extreme dendrite growth in Drosophila sensory neurons.
Genes & development - 1 Jun 2015
Lin Wen-Yang, Williams Claire, Yan Connie, Koledachkina Tatyana, Luedke Kory, Dalton Jesse, Bloomsburg Sam, Morrison Nicole, Duncan Kent E, Kim Charles C, Parrish Jay Z
Abstract excerpt
Dendrites exhibit enormous diversity in form and can differ in size by several orders of magnitude even in a single animal. However, whether neurons with large dendrite arbors have specialized mechanisms to support their growth demands is unknown. To address this question, we conducted a genetic screen for mutations that differentially affected growth in neurons with different-sized dendrite arbors. From this...
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