Article
Primary immunodeficiency diseases in a tuberculosis endemic region: challenges and opportunities.
Genes and immunity - 1 Jul 2019
Glanzmann Brigitte, Uren Caitlin, de Villiers Nikola, van Coller Ansia, Glashoff Richard H, Urban Michael, Hoal Eileen G, Esser Monika M, Möller Marlo, Kinnear Craig J
Abstract excerpt
While individual primary immunodeficiency diseases (PIDs) are rare, collectively they represent a significant burden of disease. Recent estimates show that about one million people in Africa suffer from a PID. However, data from African PID registries reflect only a small percentage of the estimated prevalence. This disparity is partly due to the lack of PID awareness and the masking of PIDs by the endemic...
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