Article
Genetic factors and risk of type 2 diabetes among women with a history of gestational diabetes: findings from two independent populations.
BMJ open diabetes research & care - 1 Jan 2020
Li Mengying, Rahman Mohammad L, Wu Jing, Ding Ming, Chavarro Jorge E, Lin Yuan, Ley Sylvia H, Bao Wei, Grunnet Louise G, Hinkle Stefanie N, Thuesen Anne Cathrine B, Yeung Edwina, Gore-Langton Robert E, Sherman Seth, Hjort Line, Kampmann Freja Bach, Bjerregaard Anne Ahrendt, Damm Peter, Tekola-Ayele Fasil, Liu Aiyi, Mills James L, Vaag Allan, Olsen Sjurdur F, Hu Frank B, Zhang Cuilin
Abstract excerpt
OBJECTIVE: Women with a history of gestational diabetes mellitus (GDM) have an exceptionally high risk for type 2 diabetes (T2D). Yet, little is known about genetic determinants for T2D in this population. We examined the association of a genetic risk score (GRS) with risk of T2D in two independent populations of women with a history of GDM and how this association might be modified by non-genetic determinants...
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