Article
An explained variance-based genetic risk score associated with gestational diabetes antecedent and with progression to pre-diabetes and type 2 diabetes: a cohort study.
BJOG : an international journal of obstetrics and gynaecology - 1 Feb 2015
Cormier H, Vigneault J, Garneau V, Tchernof A, Vohl M-C, Weisnagel S J, Robitaille J
Abstract excerpt
OBJECTIVE: To determine whether an explained-variance genetic risk score (GRS), with 36 single nucleotide polymorphisms (SNPs) previously associated with type 2 diabetes (T2D), is also associated with gestational diabetes mellitus (GDM), and with the progression to pre-diabetes and T2D among women with prior GDM. DESIGN: A cohort study. SETTING: Clinical investigation unit of Laval University, Quebec, Canada....
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