Article
Genetic determinants of gestational diabetes mellitus: a case-control study in two independent populations.
Acta diabetologica - 1 Jul 2020
Shen Yi, Jia Yulong, Li Yuandong, Gu Xuefeng, Wan Guoqing, Zhang Peng, Zhang Yafeng, Jiang Liying
Abstract excerpt
BACKGROUND: Genetic risk score (GRS) is more informative to identify the complicated associations between variants of genes and disease. Considering similar pathogenesis and shared genetic predispositions between gestational diabetes mellitus (GDM) and type 2 diabetes/obesity, we conducted this study to explore whether the GRS model integrating variants related to type 2 diabetes/obesity is also associated with...
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