Article
CCL23: A Chemokine Associated with Progression from Mild Cognitive Impairment to Alzheimer's Disease.
Journal of Alzheimer's disease : JAD - 1 Jan 2020
Faura Júlia, Bustamante Alejandro, Penalba Anna, Giralt Dolors, Simats Alba, Martínez-Sáez Elena, Alcolea Daniel, Fortea Juan, Lleó Alberto, Teunissen Charlotte E, van der Flier Wiesje M, Ibañez Laura, Harari Oscar, Cruchaga Carlos, Hernández-Guillamón Mar, Delgado Pilar, Montaner Joan
Abstract excerpt
CCL23 is a chemokine implicated in inflammation and host defense responses. It has been recently associated with acquired brain damage and stroke outcomes. In this study, we reported the role of CCL23 in Alzheimer's disease (AD). We evaluated the levels of CCL23 in 659 individuals: cognitively normal, mild cognitive impaired (MCI), and AD patients. Two cross-sectional (study 1, n = 53; study 2, n = 200) and two...
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