Article
Increased serum IL-1beta level in Alzheimer's disease and mild cognitive impairment.
Dementia and geriatric cognitive disorders - 1 Jan 2009
Forlenza Orestes Vicente, Diniz Breno Satler, Talib Leda Leme, Mendonça Vanessa Amaral, Ojopi Elida B, Gattaz Wagner Farid, Teixeira Antonio Lucio
Abstract excerpt
BACKGROUND/AIMS: Abnormal inflammatory response has been associated to the pathogenesis of Alzheimer's disease (AD) and may be a marker of an ongoing neurodegenerative process. The aim of this study was to evaluate the serum levels of interleukin-1beta (IL-1beta) in patients with mild cognitive impairment (MCI) and AD. METHODS: One hundred and sixty-three older adults (58 with mild to moderate AD, 74 with MCI and...
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