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Article

A focus on CXCR4 in Alzheimer's disease

1 Jan 2017

Abstract excerpt

Alzheimer's disease (AD) is one of the most common and devastating aging-related neurodegenerative diseases. Besides the well-known role of chemokines and their receptors in the immune system, they are widely expressed in the nervous system, where they play roles in the regulation of cell migration and neurotransmission. The chemokine CXC motif receptor 4 (CXCR4) is evolutionarily highly conserved...

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PMID: 30276325
DOI: 10.4103/bc.bc_13_17

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