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Article

Recent positive selection signatures reveal phenotypic evolution in the Han Chinese population.

Science bulletin - 30 Oct 2023

Luo Huaxia, Zhang Peng, Zhang Wanyu, Zheng Yu, Hao Di, Shi Yirong, Niu Yiwei, Song Tingrui, Li Yanyan, Zhao Shilei, Chen Hua, Xu Tao, He Shunmin

Abstract excerpt

Characterizing natural selection signatures and relationships with phenotype spectra is important for understanding human evolution and both biological and pathological mechanisms. Here, we identified 24 genetic loci under recent selection by analyzing rare singletons in 3946 high-depth whole-genome sequencing data of Han Chinese. The loci include immune-related gene regions (MHC cluster, IGH cluster, STING1, and...

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PMID: 37661541
DOI: 10.1016/j.scib.2023.08.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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