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Article

Genetic variation in DNA repair pathway genes and melanoma risk.

DNA repair - 2 Jan 2011

Zhang Mingfeng, Qureshi Abrar A, Guo Qun, Han Jiali

Abstract excerpt

Reduced DNA repair capacity has been proposed as a predisposing factor for melanoma. We comprehensively evaluated 1463 genetic variants across 60 DNA repair-related pathway genes in relation to melanoma risk in a nested case-control study of 218 melanoma cases (20% on head and neck) and 218 matched controls within the Nurses' Health Study (NHS). We then genotyped the two variants with the smallest P value in two...

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Source

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Identifiers

PMID: 20837404
DOI: 10.1016/j.dnarep.2010.08.005
PMCID: PMC3010342

Genes

NHS
PARP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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