Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variants in glutamine metabolic pathway genes predict cutaneous melanoma-specific survival.

Molecular carcinogenesis - 1 Nov 2019

Chen Ka, Liu Hongliang, Liu Zhensheng, Bloomer Wendy, Amos Christopher I, Lee Jeffrey E, Li Xin, Nan Hongmei, Wei Qingyi

Abstract excerpt

Glutamine dependence is a unique metabolic defect seen in cutaneous melanoma (CM), directly influencing the treatment and prognosis. Here, we investigated the associations between 6025 common single-nucleotide polymorphisms (SNPs) in 77 glutamine metabolic pathway genes with CM-specific survival (CMSS) using genotyping datasets from two published genome-wide association studies (GWASs). In the single-locus...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease-Free Survival

Share to Genome-Wide Association Study

Share to Glutamine

Share to Melanoma

Share to Metabolic Networks and Pathways

Share to Skin Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 31435991
DOI: 10.1002/mc.23100
PMCID: PMC7504905

Genes

HAL
LGSN
NOXRED1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variants in glutamine metabolic pathway genes predict cutaneous melanoma-specific survival.PMID 31435991Read ↗

Genetic variants in PDSS1 and SLC16A6 of the ketone body metabolic pathway predict cutaneous melanoma-specific survival.Semantic proximity Read ↗

Genetic variants in the folate metabolic pathway genes predict cutaneous melanoma-specific survival.Semantic proximity Read ↗

Single-cell RNA-sequencing analyses along with abundant machine learning methods develop and validate a novel metabolism-related prognostic model in SKCMSemantic proximity Read ↗

A glycolysis-related lncRNAs signature for predicting prognosis and evaluating the tumor immune microenvironment of cutaneous melanomaSemantic proximity Read ↗

Unravelling the metabolic landscape of cutaneous melanoma: Insights from single-cell sequencing analysis and machine learning for prognostic assessment of lactate metabolism.Semantic proximity Read ↗

Identification of lactylation gene CALML5 and its correlated lncRNAs in cutaneous melanoma by machine learningSemantic proximity Read ↗

Glutamine metabolism model for predicting prognosis and immune infiltration in laryngeal squamous cell carcinomaSemantic proximity Read ↗

Genomic subtypes of cutaneous melanoma have distinct metabolic profiles: A single-cell transcriptomic analysis.Semantic proximity Read ↗

Genetic variants in ELOVL2 and HSD17B12 predict melanoma-specific survival.Semantic proximity Read ↗

Glutamine Metabolism Scoring Predicts Prognosis and Therapeutic Resistance in Hepatocellular CarcinomaSemantic proximity Read ↗

Genetic variants of SDCCAG8 and MAGI2 in mitosis-related pathway genes are independent predictors of cutaneous melanoma-specific survival.Semantic proximity Read ↗

Integrative genomics identifies molecular alterations that challenge the linear model of melanoma progression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.