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Article

Evolving Significance of Tumor-Normal Sequencing in Cancer Care.

Trends in cancer - 1 Jan 2020

Mandelker Diana, Ceyhan-Birsoy Ozge

Abstract excerpt

Molecular tests assist at various stages of cancer patient management, including providing diagnosis, predicting prognosis, identifying therapeutic targets, and determining hereditary cancer risk. The current testing paradigm involves germline testing in a subset of patients determined to be at high risk for having a hereditary cancer syndrome, and tumor-only sequencing for treatment decisions in advanced cancer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31952779
DOI: 10.1016/j.trecan.2019.11.006
PMCID: PMC8923150

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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