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Article

Germline Findings in Tumor-Only Sequencing: Points to Consider for Clinicians and Laboratories.

Journal of the National Cancer Institute - 1 Apr 2016

Raymond Victoria M, Gray Stacy W, Roychowdhury Sameek, Joffe Steve, Chinnaiyan Arul M, Parsons D Williams, Plon Sharon E

Abstract excerpt

Precision oncology holds great potential to improve patient therapies and outcomes. Tumor sequencing is rapidly moving into clinical care as our understanding of the cancer genome and the availability of targeted therapies increase. Analysis of the cancer genome is most informative when paired with germline genomic DNA to delineate inherited and somatic variants. Although tumor-only analysis remains the most...

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Identifiers

PMID: 26590952
DOI: 10.1093/jnci/djv351
PMCID: PMC4849259

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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