Article
GPCRsignal: webserver for analysis of the interface between G-protein-coupled receptors and their effector proteins by dynamics and mutations.
Nucleic acids research - 2 Jul 2021
Miszta Przemysław, Pasznik Paweł, Niewieczerzał Szymon, Jakowiecki Jakub, Filipek Sławomir
Abstract excerpt
GPCRsignal (https://gpcrsignal.biomodellab.eu/) is a webserver devoted to signaling complexes of G-protein-coupled receptors (GPCRs). The recent improvement in cryo-electron microscopy resulted in the determination of a large number of high-resolution structures of GPCRs bound to their effector proteins: G proteins or arrestins. Analyzing the interfaces between receptor and an effector protein is of high...
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