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Article

Prediction of heterodimerization interfaces of G-protein coupled receptors with a new subtractive correlated mutation method.

Protein engineering - 1 Nov 2002

Filizola Marta, Olmea Osvaldo, Weinstein Harel

Abstract excerpt

Recent studies employing differential epitope tagging, selective immunoprecipitation of receptor complexes and fluorescence or bioluminescence resonance energy transfer techniques provide direct evidence for heterodimerization between both closely and distantly related members of the G-protein coupled receptor (GPCR) family. Since heterodimerization appears to play a role in modulating agonist affinity, efficacy...

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PMID: 12538907
DOI: 10.1093/protein/15.11.881

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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