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Article

Proprotein convertase 7 (PCSK7) reduces apoA-V levels.

The FEBS journal - 1 Aug 2020

Ashraf Yahya, Duval Stéphanie, Sachan Vatsal, Essalmani Rachid, Susan-Resiga Delia, Roubtsova Anna, Hamelin Josée, Gerhardy Stefan, Kirchhofer Daniel, Tagliabracci Vincent S, Prat Annik, Kiss Robert Scott, Seidah Nabil G

Abstract excerpt

The locus of the human proprotein convertase subtilisin-kexin type-7 (PC7) gene (PCSK7) is on chromosome 11q23.3 close to the gene cluster APOA5/APOA4/APOC3/APOA1, a region implicated in the regulation of lipoprotein metabolism. A GWAS reported the association of PCSK7 SNPs with plasma triglyceride (TG), and exome sequencing of African Americans revealed the association of a low-frequency coding variant of PC7...

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Identifiers

PMID: 31945259
DOI: 10.1111/febs.15212

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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