Article
Effect of single-nucleotide polymorphism in TERT promoter on follicular thyroid tumor development.
Pathology international - 1 Apr 2020
Hirokawa Tatsuya, Arimasu Yuu, Nakazato Yoko, Chiba Tomohiro, Fujiwara Masachika, Kamma Hiroshi
Abstract excerpt
Follicular thyroid neoplasm is a common tumor, and consists of follicular thyroid adenoma (FTA) and carcinoma (FTC). The mechanisms of tumor development of FTA and FTC are not well-understood. Single-nucleotide polymorphisms (SNPs) and point mutations in the telomerase reverse transcriptase (TERT) promoter have been associated with tumor development of many cancers. In order to clarify the significance of TERT...
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