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Article

TERT promoter mutation as an early genetic event activating telomerase in follicular thyroid adenoma (FTA) and atypical FTA.

Cancer - 1 Oct 2014

Wang Na, Liu Tiantian, Sofiadis Anastasios, Juhlin C Christofer, Zedenius Jan, Höög Anders, Larsson Catharina, Xu Dawei

Abstract excerpt

BACKGROUND: The telomerase reverse transcriptase (TERT) promoter mutations C228T and C250T have been found in many malignancies, including in thyroid carcinomas. However, it is unclear how early these mutations occur in thyroid tumorigenesis. METHODS: The study included primary tumors from 58 pat...

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Source

Identifiers

PMID: 24898513
DOI: 10.1002/cncr.28800

Genes

TERT
NRAS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24898513-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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