Article
TERT promoter mutations and their association with BRAF V600E mutation and aggressive clinicopathological characteristics of thyroid cancer.
The Journal of clinical endocrinology and metabolism - 1 Jun 2014
Liu Xiaoli, Qu Shen, Liu Rengyun, Sheng Chunjun, Shi Xiaoguang, Zhu Guangwu, Murugan Avaniyapuram Kannan, Guan Haixia, Yu Hongyu, Wang Yangang, Sun Hui, Shan Zhongyan, Teng Weiping, Xing Mingzhao
Abstract excerpt
CONTEXT: Promoter mutations chr5:1,295,228C>T and chr5:1,295,250C>T (termed C228T and C250T, respectively) in the gene for telomerase reverse transcriptase (TERT) have been reported in various cancers and need to be further investigated in thyroid cancer. OBJECTIVE: The aim of the study was to explore TERT promoter mutations in various thyroid tumors and examine their relationship with BRAF V600E mutation, iodine...
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