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Article

Progesterone Receptor Gene Variants in Metastatic Estrogen Receptor Positive Breast Cancer.

Hormones & cancer - 1 Apr 2020

Fowler Amy M, Salem Kelley, DeGrave Michael, Ong Irene M, Rassman Shane, Powers Ginny L, Kumar Manoj, Michel Ciara J, Mahajan Aparna M

Abstract excerpt

Tumor mutations in the gene encoding estrogen receptor alpha (ESR1) have been identified in metastatic breast cancer patients with endocrine therapy resistance. However, relatively little is known about the occurrence of mutations in the progesterone receptor (PGR) gene in this population. The study objective was to determine the frequency and prognostic significance of tumor PGR mutations for patients with...

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Source

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Identifiers

PMID: 31942683
DOI: 10.1007/s12672-020-00377-3
PMCID: PMC7152560

Genes

PGR
ESR1
MB

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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