Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

B Cell-Specific Transcription Activator PAX5 Recruits p300 To Support EBNA1-Driven Transcription.

Journal of virology - 17 Mar 2020

Liu Cheng-Der, Lee Hsueh-Ling, Peng Chih-Wen

Abstract excerpt

The binding of Epstein-Barr Virus (EBV) nuclear antigen 1 (EBNA1) to the latent replication origin (oriP) triggers multiple downstream events to support virus-induced pathogenesis and tumorigenesis. Although EBV is widely recognized as a B-lymphotropic infectious agent, little is known about how tissue-specific factors are involved in the establishment of latency. Here, we showed that EBNA1 binds B cell activator...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to E1A-Associated p300 Protein
Share to Epstein-Barr Virus Infections

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epstein-Barr Virus Nuclear Antigens

Share to Gene Expression Regulation, Viral

Share to Herpesvirus 4, Human

Share to PAX5 Transcription Factor

Share to Protein Interaction Maps

Share to Replication Origin

Source

Open in PubMed Open full text

Identifiers

PMID: 31941781
DOI: 10.1128/JVI.02028-19
PMCID: PMC7081918

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

B Cell-Specific Transcription Activator PAX5 Recruits p300 To Support EBNA1-Driven Transcription.PMID 31941781Read ↗

Impact of EBV Essential Nuclear Protein EBNA-3C on B-Cell Proliferation and ApoptosisSemantic proximity Read ↗

The B-Cell-Specific Transcription Factor and Master Regulator Pax5 Promotes Epstein-Barr Virus Latency by Negatively Regulating the Viral Immediate Early Protein BZLF1Semantic proximity Read ↗

The Linking Regions of EBNA1 Are Essential for Its Support of Replication and TranscriptionSemantic proximity Read ↗

HCF1 and OCT2 Cooperate with EBNA1 To Enhance OriP-Dependent Transcription and Episome Maintenance of Latent Epstein-Barr VirusSemantic proximity Read ↗

DNA methylation enzymes and PRC1 restrict B-cell Epstein–Barr virus oncoprotein expressionSemantic proximity Read ↗

Epstein-Barr Virus Episome Physically Interacts with Active Regions of the Host Genome in Lymphoblastoid CellsSemantic proximity Read ↗

The Epstein-Barr Virus EBNA1 ProteinSemantic proximity Read ↗

Identification of <i>MEF2B</i> , <i>EBF1</i> , and <i>IL6R</i> as Direct Gene Targets of Epstein-Barr Virus (EBV) Nuclear Antigen 1 Critical for EBV-Infected B-Lymphocyte SurvivalSemantic proximity Read ↗

EBNA1-Mediated Recruitment of a Histone H2B Deubiquitylating Complex to the Epstein-Barr Virus Latent Origin of DNA ReplicationSemantic proximity Read ↗

The Cooperative Functions of the EBNA3 Proteins Are Central to EBV Persistence and LatencySemantic proximity Read ↗

Histone acetyltransferase p300 acetylates Pax5 and strongly enhances Pax5-mediated transcriptional activity.Semantic proximity Read ↗

CpG-Methylation Regulates a Class of Epstein-Barr Virus PromotersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.