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Article

Poorly differentiated thyroid carcinoma of childhood and adolescence: a distinct entity characterized by DICER1 mutations.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jul 2020

Chernock Rebecca D, Rivera Barbara, Borrelli Nicla, Hill D Ashley, Fahiminiya Somayyeh, Shah Tasha, Chong Anne-Sophie, Aqil Barina, Mehrad Mitra, Giordano Thomas J, Sheridan Rachel, Rutter Meilan M, Dehner Louis P, Foulkes William D, Nikiforov Yuri E

Abstract excerpt

Poorly differentiated thyroid carcinomas (PDTC) in young individuals are rare and their clinical and histopathologic features, genetic mechanisms, and outcomes remain largely unknown. Here, we report a detailed characterization of a series of six PDTC in patients ≤21 years old defined by Turin diagnostic criteria studied for mutations and gene fusions characteristic of thyroid cancer using targeted...

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Identifiers

PMID: 31937902
DOI: 10.1038/s41379-020-0458-7
PMCID: PMC7329587

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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