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Clinicopathologic and Molecular Analysis of 15 Pediatric and Young Adult Patients with High-Grade Non-anaplastic Thyroid Carcinoma.

Endocrine pathology - 1 Dec 2024

Whaley Rumeal D, Gupta Sounak, Manninen Matthew C, O'Brien Daniel R, Erickson Lori A

Abstract excerpt

High-grade follicular cell-derived non-anaplastic thyroid carcinomas are uncommon and typically diagnosed in the sixth to seventh decade of life. These tumors are rare in the pediatric (≤ 18 years old) and young adult (19-21 years old) populations. The molecular landscape of pediatric and young adult thyroid neoplasia has been suggested to be enriched in DICER1 gene alterations. Our intent was to evaluate...

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PMID: 39636536
DOI: 10.1007/s12022-024-09842-z

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