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Article

DICER1 Mutations Are Frequent in Adolescent-Onset Papillary Thyroid Carcinoma.

The Journal of clinical endocrinology and metabolism - 1 May 2018

Wasserman Jonathan D, Sabbaghian Nelly, Fahiminiya Somayyeh, Chami Rose, Mete Ozgur, Acker Meryl, Wu Mona K, Shlien Adam, de Kock Leanne, Foulkes William D

Abstract excerpt

Context: Papillary thyroid carcinoma (PTC) is a common malignancy in adolescence and is molecularly and clinically distinct from adult PTC. Mutations in the DICER1 gene are associated with thyroid abnormalities, including multinodular goiter and differentiated thyroid carcinoma. Objective: In this study, we sought to characterize the prevalence of DICER1 variants in pediatric PTC, specifically in tumors without...

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Age of Onset
Child
DEAD-box RNA Helicases
Gene Dosage
Gene Frequency

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Ribonuclease III

Thyroid Cancer, Papillary

Source

Identifiers

PMID: 29474644
DOI: 10.1210/jc.2017-02698

Genes

DICER1
RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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DICER1 Mutations Are Frequent in Adolescent-Onset Papillary Thyroid Carcinoma.PMID 29474644Read ↗

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