Article
DICER1 Mutations Do Not Always Indicate Dismal Prognosis in Pediatric Poorly Differentiated Thyroid Carcinomas.
Endocrine pathology - 1 Sept 2023
Yegen Gülçin, Altay Ali Yılmaz, Yılmaz İsmail, İşcan Yalın, Sormaz İsmail Cem, Aksakal Nihat, Önder Semen, Mete Özgür
Abstract excerpt
Progress in the field of pediatric thyroid pathology has linked DICER1 mutations to benign follicular cell-derived thyroid tumors (e.g., follicular adenoma with papillary architecture, follicular nodular disease), low-risk follicular cell-derived differentiated thyroid carcinomas and PDTCs enriched in fatal or recurrent/progressive disease. The dismal outcome of DICER1-harboring pediatric PDTCs stems from a...
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